European Li Fraumeni Foundation

Find your way for support in Europe


For a Live Webinar on LFS & COVID-19Friday, March 27th at 4-5pm ET The LFS Association and Dr. Joshua Schiffman from the Huntsman Cancer Institute will be hosting a special webinar for families with Li-Fraumeni syndrome to share insights on the COVID-19 virus and how it affects the LFS community.If you have any questions for Dr. Joshua Schiffan you can […]

Cancer patients and the coronavirus:

There are seven things cancer patients should know about coronaviruses, including the 2019 novel coronavirus disease (COVID-19) that was first detected in Hubei province, China. What is a coronavirus? Human coronaviruses are a family of viruses that are found throughout the world. There are seven known types. Four of those types (229E, NL63, OC43 and HKU1) cause only mild or moderate upper-respiratory illness, […]

Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents. And corona?

Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents. And corona? Verbaanderd C1,2,3, Maes H2, Schaaf MB2, Sukhatme VP4,5, Pantziarka P1,6, Sukhatme V4, Agostinis P2, Bouche G1. Author information Abstract Source: Pubmed Chloroquine (CQ) and hydroxychloroquine (HCQ) are well-known 4-aminoquinoline antimalarial agents. Scientific evidence also supports the use of CQ and HCQ in the treatment of cancer. Overall, preclinical studies support CQ and HCQ use in […]

300 Anticancer drugs

NEWS – The Anticancer Fund has identified 300 drugs with the potential to be used as new cancer treatments. These drugs are on the market to treat other diseases, but they’ve shown evidence of anti-cancer effects in laboratory experiments or in people. Further research is necessary, but these drugs could potentially increase the survival of cancer patients.The 300 drugs are […]

Working on ‘the human side’ of heritable cancers OPEN NAVIGATION

I love working with people,” says Allison Werner-Lin of the School of Social Policy & Practice (SP2). Werner-Lin’s office overlooking Locust Walk is homey and lamp-lit, with student gifts sharing space with scholarly tomes. This is just one of her workspaces, however. Recently returned from sabbatical, Werner-Lin has been working with the National Cancer Institute (NCI), as well as out of her home in upstate New […]

Prime editing: DNA tool could correct 89% of genetic defects

Source BBCA new way of editing the code of life could correct 89% of the errors in DNA that cause disease, say US scientists.The technology, called prime editing, has been described as a “genetic word processor” able to accurately re-write the genetic code. It has been used to correct damaging mutations in the lab, including those that cause sickle cell […]

What is Li-Fraumeni Syndrome? | Dana-Farber Cancer Institute

E02.1 From Li-Fraumeni syndrome to TP53-related inherited cancers

Quote of the week

If you cannot do great things, do small things in a great way. Napoleon Hill

Quote of the day

“Courage is not the absence of fear, but rather the judgement that something else is more important than fear” ~ Ambrose Redmoon

What is Li Fraumeni?

Li-Fraumeni syndrome  rare, inherited disorder that is caused by mutations (changes) in the TP53 gene. Having Li-Fraumeni syndrome increases the risk of developing many types of cancer. Cancers often develop at an early age, and more than one type of cancer may occur in the same person. Li-Fraumeni syndrome is a type of hereditary cancer syndrome. Also called LFS.
or LFS-like syndrome

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